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1

P2RY1 and P2RY12 polymorphisms and on-aspirin platelet reactivity in patients with coronary artery disease

A. A. TIMUR, G. MURUGESAN, L. ZHANG, P. P. AUNG, J. BARNARD, Q. K. WANG, P. GAUSSEM, R. L. SILVERSTEIN, D. L. BHATT, K. KOTTKE-MARCHANT

Journal:

International Journal of Laboratory Hematology (Blackwell)

Year:

2012

Language:

english

File:

PDF, 132 KB

english, 2012

2

Infections et inflammations

J.-L. Diehl, D. Borgel, P. Gaussem, D. Smadja

Journal:

Médecine Intensive Réanimation

Year:

2013

Language:

french

File:

PDF, 848 KB

french, 2013

3

Carmat Bioprosthetic Total Artificial Heart is Associated With An Early Hemostatic Recovery and No Acquired Willebrand Syndrome in Calves

Smadja, David M., Susen, Sophie, Rauch, Antoine, Cholley, Bernard, Latrémouille, Christian, Duveau, Daniel, Zilberstein, Luca, Méléard, Denis, Boughenou, Marie-Fazia, Belle, Eric Van, Gaussem, Pascale

Journal:

Journal of Cardiothoracic and Vascular Anesthesia

Year:

2017

Language:

english

File:

PDF, 1.36 MB

english, 2017

4

Evidence that MRP4 is Only Partly Involved in S1P Secretion during Platelet Activation

Decouture, Benoit, Becker, Pierre-Hadrien, Therond, Patrice, Gaussem, Pascale, Bachelot-Loza, Christilla

Journal:

Thrombosis and Haemostasis

Year:

2018

Language:

english

File:

PDF, 91 KB

english, 2018

5

Bone-marrow-derived very small embryonic-like stem cells in patients with critical leg ischaemia: evidence of vasculogenic potential

Guerin, Coralie L., Loyer, Xavier, Vilar, José, Cras, Audrey, Mirault, Tristan, Gaussem, Pascale, Silvestre, Jean-Sébastien, Smadja, David M.

Journal:

Thrombosis and Haemostasis

Year:

2015

Language:

english

File:

PDF, 1.64 MB

english, 2015

6

Modified ROTEM for the detection of rivaroxaban and apixaban anticoagulant activity in whole blood

Pailleret, Claire, Jourdi, Georges, Siguret, Virginie, Gouin-Thibault, Isabelle, Gandrille, Sophie, Stepanian, Alain, Curis, Emmanuel, Golmard, Jean-Louis, Gaussem, Pascale, Le Bonniec, Bernard, Samam

Journal:

European Journal of Anaesthesiology

Year:

2018

Language:

english

File:

PDF, 790 KB

english, 2018

7

Rivaroxaban pharmacodynamics in healthy volunteers evaluated with thrombin generation and the active protein C system: modeling and assessing inter-individual variability

Siguret, Virginie, Abdoul, Johan, Delavenne, Xavier, Curis, Emmanuel, Carlo, Audrey, Blanchard, Anne, Salem, Joe-Elie, Gaussem, Pascale, Funck-Brentano, Christian, Azizi, Michel, Mismetti, Patrick, Lo

Journal:

Journal of Thrombosis and Haemostasis

Year:

2019

Language:

english

File:

PDF, 640 KB

english, 2019

8

Endothelial progenitor cells are selectively mobilised immediately after coronary artery bypass grafting or valve surgery

Smadja, David, Godier, Anne, Susen, Sophie, Packard, René, Fabiani, Jean-Noël, Aiach, Martine, Gaussem, Pascale

Journal:

Thrombosis and Haemostasis

Year:

2009

File:

PDF, 71 KB

2009

9

Platelet Functions During Extracorporeal Membrane Oxygenation. PlateletâLeukocyte Aggregates Analyzed by Flow Cytometry as a Promising Tool to Monitor Platelet Activation

Mansour, Alexandre, Roussel, Mikael, Gaussem, Pascale, NÃ©delec-Gac, Fabienne, Pontis, Adeline, FlÃ©cher, Erwan, Bachelot-Loza, Christilla, Gouin-Thibault, Isabelle

Journal:

Journal of Clinical Medicine

Year:

2020

File:

PDF, 1.57 MB

2020

10

Serum antibodies to distinct epitopes of the tissue-type plasminogen activator (t-PA) in patients with systemic lupus erythematosus

Alejandro Ruiz-Arguelles, Eduardo Angles-Cano, Beatriz Perez-Romano, Guillermo J. Ruiz-Arguelles, Margarita Deleze, Donato Alarcon-Segovia, Pascale Gaussem

Journal:

American Journal of Hematology

Year:

1995

Language:

english

File:

PDF, 586 KB

english, 1995

11

Les médicaments anti-plaquettaires

Poascale Gaussem

Journal:

Revue Francophone des Laboratoires

Year:

2006

File:

PDF, 3.13 MB

2006

12

Dose-effect relationship for several coagulation markers during administration of the direct thrombin inhibitor S 18326 in healthy subjects

P. Gaussem, M. Dubar, B. Le Bonniec, I. Richard-Lordereau, R. Jochemsen, M. Aiach

Journal:

British Journal of Clinical Pharmacology

Year:

2002

Language:

english

File:

PDF, 132 KB

english, 2002

13

Comparison of Endothelial Biomarkers According to Reversibility of Pulmonary Hypertension Secondary to Congenital Heart Disease

David M. Smadja, Pascale Gaussem, Laetitia Mauge, Romaric Lacroix, Sophie Gandrille, Véronique Remones, Séverine Peyrard, Florence Sabatier, Damien Bonnet, Marilyne Lévy

Journal:

Pediatric Cardiology

Year:

2010

Language:

english

File:

PDF, 198 KB

english, 2010

14

Treprostinil increases the number and angiogenic potential of endothelial progenitor cells in children with pulmonary hypertension

David M. Smadja, Laetitia Mauge, Pascale Gaussem, Clément d’Audigier, Dominique Israel-Biet, David S. Celermajer, Damien Bonnet, Marilyne Lévy

Journal:

Year:

2011

Language:

english

File:

PDF, 468 KB

english, 2011

15

Endothelial progenitor cells: Characterization,in vitroexpansion, and prospects for autologous cell therapy

D. M. Smadja, A. Cornet, J. Emmerich, M. Aiach, P. Gaussem

Journal:

Cell Biology and Toxicology

Year:

2007

Language:

english

File:

PDF, 567 KB

english, 2007

16

Platelet receptor gain-of-function single nucleotide polymorphisms in carotid and vertebral stenosis patients

Andrea Kopp Lugli, Martin M. Brown, Jan Steffel, Linda Büchi, Dorothee Förnzler, Annabelle Dupont, Pascale Gaussem, Marc Forestier, Juerg H. Beer

Journal:

Journal of Thrombosis and Thrombolysis

Year:

2011

Language:

english

File:

PDF, 276 KB

english, 2011

17

Antiplatelet and antithrombotic effect of F 16618, a new thrombin proteinase-activated receptor-1 (PAR1) antagonist

M Dumas, F Nadal-Wollbold, P Gaussem, M Perez, T Mirault, R Létienne, T Bourbon, F Grelac, B Le Grand, C Bachelot-Loza

Journal:

British Journal of Pharmacology

Year:

2012

Language:

english

File:

PDF, 673 KB

english, 2012

18

Tissue factor expression and P2Y12 gene polymorphism

J-L. Reny, P. Gaussem, V. Remones, J. Emmerich, P. Fontana

Journal:

Journal of Thrombosis and Haemostasis

Year:

2004

Language:

english

File:

PDF, 92 KB

english, 2004

19

LETTER TO THE EDITOR: P2Y1 gene polymorphism and ADP-induced platelet response

P. FONTANA, V. REMONES, J.-L. RENY, M. AIACH, P. GAUSSEM

Journal:

Journal of Thrombosis and Haemostasis

Year:

2005

Language:

english

File:

PDF, 99 KB

english, 2005

20

The specific thromboxane receptor antagonist S18886: pharmacokinetic and pharmacodynamic studies

P. GAUSSEM, J.-L. RENY, C. THALAMAS, N. CHATELAIN, M. KROUMOVA, B. JUDE, B. BONEU, J.-N. FIESSINGER

Journal:

Journal of Thrombosis and Haemostasis

Year:

2005

Language:

english

File:

PDF, 316 KB

english, 2005

21

The angiopoietin pathway is modulated by PAR-1 activation on human endothelial progenitor cells

D. M. SMADJA, I. LAURENDEAU, C. AVIGNON, M. VIDAUD, M. AIACH, P. GAUSSEM

Journal:

Journal of Thrombosis and Haemostasis

Year:

2006

Language:

english

File:

PDF, 695 KB

english, 2006

22

Role of the P2Y12 gene polymorphism in platelet responsiveness to clopidogrel in healthy subjects

A. BURA, C. BACHELOT-LOZA, F. Dali ALI, M. AIACH, P. GAUSSEM

Journal:

Journal of Thrombosis and Haemostasis

Year:

2006

Language:

english

File:

PDF, 520 KB

english, 2006

23

PAR-1 activation has different effects on the angiogenic activity of endothelial progenitor cells derived from human adult and cord blood

D. M. SMADJA, I. BIÈCHE, J. EMMERICH, M. AIACH, P. GAUSSEM

Journal:

Journal of Thrombosis and Haemostasis

Year:

2006

Language:

english

File:

PDF, 125 KB

english, 2006

24

Influence of CYP2C19 and CYP3A4 gene polymorphisms on clopidogrel responsiveness in healthy subjects

P. FONTANA, J.-S. HULOT, P. DE MOERLOOSE, P. GAUSSEM

Journal:

Journal of Thrombosis and Haemostasis

Year:

2007

Language:

english

File:

PDF, 498 KB

english, 2007

25

Blood outgrowth endothelial cells from cord blood and peripheral blood: angiogenesis-related characteristics in vitro: a rebuttal

D. M. SMADJA, L. MAUGE, S. SUSEN, I. BIECHE, P. GAUSSEM

Journal:

Journal of Thrombosis and Haemostasis

Year:

2009

Language:

english

File:

PDF, 113 KB

english, 2009

26

Elevated plasma fibrin D-dimer as a risk factor for vascular dementia: the Three-City cohort study

L. CARCAILLON, P. GAUSSEM, P. DUCIMETIÈRE, M. GIROUD, K. RITCHIE, J. F. DARTIGUES, P. Y. SCARABIN

Journal:

Journal of Thrombosis and Haemostasis

Year:

2009

Language:

english

File:

PDF, 127 KB

english, 2009

27

Effect of an increased clopidogrel maintenance dose or lansoprazole co-administration on the antiplatelet response to clopidogrel in CYP2C19-genotyped healthy subjects

J.-S. HULOT, G. WUERZNER, C. BACHELOT-LOZA, M. AZIZI, A. BLANCHARD, S. PEYRARD, C. FUNCK-BRENTANO, P. GAUSSEM

Journal:

Journal of Thrombosis and Haemostasis

Year:

2010

Language:

english

File:

PDF, 175 KB

english, 2010

28

The minor allele of GP6 T13254C is associated with decreased platelet activation and a reduced risk of recurrent cardiovascular events and mortality: results from the SMILE–Platelets project

J. D. SNOEP, P. GAUSSEM, J. C. J. EIKENBOOM, J. EMMERICH, J. J. ZWAGINGA, C. E. HOLMES, H. L. VOS, PH. G. DE GROOT, D. M. HERRINGTON, P. F. BRAY, F. R. ROSENDAAL, J. G. VAN DER BOM

Journal:

Journal of Thrombosis and Haemostasis

Year:

2010

Language:

english

File:

PDF, 194 KB

english, 2010

29

Bone marrow-derived mononuclear cell therapy induces distal angiogenesis after local injection in critical leg ischemia

Van Huyen, Jean-Paul Duong, Smadja, David M, Bruneval, Patrick, Gaussem, Pascale, Dal-Cortivo, Liliane, Julia, Pierre, Fiessinger, Jean-Noël, Cavazzana-Calvo, Marina, Aiach, Martine, Emmerich, Joseph

Journal:

Modern Pathology

Year:

2008

Language:

english

File:

PDF, 823 KB

english, 2008

30

Identification of Protein C Epitopes Altered During Its Nanoencapsulation

D. Chognot, M. F. Zambaux, F. Bonneaux, P. Gaussem, J. L. Pittet, M. Aiach, C. Vigneron

Journal:

The Protein Journal

Year:

1999

Language:

english

File:

PDF, 505 KB

english, 1999

31

The formation of complexes between human plasminogen activator inhibitor-1 (PAI-1) and sodium dodecyl sulfate: possible implication in the functional properties of PAI-1

Pascale Gaussem, Eduardo Anglés-Cano

Journal:

Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology

Year:

1991

Language:

english

File:

PDF, 1.05 MB

english, 1991

32

Effect of clopidogrel on circulating biomarkers of angiogenesis and endothelial activation

David M. Smadja, Alessandra Bura, Jean Szymezak, Anne Blanchard, Véronique Remones, Michel Azizi, Pascale Gaussem

Journal:

Journal of Cardiology

Year:

2012

Language:

english

File:

PDF, 359 KB

english, 2012

33

Increase in expression and activity of thrombomodulin in term human syncytiotrophoblast microvilli

A. Fazel, A. Vincenot, A. Malassiné, F. Soncin, P. Gaussem, E. Alsat, D. Evain-Brion

Journal:

Year:

1998

Language:

english

File:

PDF, 12.79 MB

english, 1998

34

The profibrotic cytokine transforming growth factor-β1 increases endothelial progenitor cell angiogenic properties

S. M. EVRARD, C. D′AUDIGIER, L. MAUGE, D. ISRAËL-BIET, C. L. GUERIN, I. BIECHE, J. C. KOVACIC, A.-M. FISCHER, P. GAUSSEM, D. M. SMADJA

Journal:

Journal of Thrombosis and Haemostasis

Year:

2012

Language:

english

File:

PDF, 558 KB

english, 2012

35

Vascular endothelial growth factor, as compared with placental growth factor, is increased in severe sepsis but not in organ failure

D. M. SMADJA, D. BORGEL, J.-L. DIEHL, P. GAUSSEM

Journal:

Journal of Thrombosis and Haemostasis

Year:

2012

Language:

english

File:

PDF, 150 KB

english, 2012

36

Increased VEGFR2 expression during human late endothelial progenitor cells expansion enhances in vitro angiogenesis with up-regulation of integrin α6

David M. Smadja, Ivan Bièche, Dominique Helley, Ingrid Laurendeau, Ghislaine Simonin, Laurent Muller, Martine Aiach, Pascale Gaussem

Journal:

Journal of Cellular and Molecular Medicine

Year:

2007

Language:

english

File:

PDF, 343 KB

english, 2007

37

Thrombin bound to a fibrin clot confers angiogenic and haemostatic properties on endothelial progenitor cells

David M. Smadja, Agnès Basire, Aymeric Amelot, Aurélie Conte, Ivan Bièche, Bernard F. Le Bonniec, Martine Aiach, Pascale Gaussem

Journal:

Journal of Cellular and Molecular Medicine

Year:

2008

Language:

english

File:

PDF, 390 KB

english, 2008

38

Interleukin 8 is differently expressed and modulated by PAR-1 activation in early and late endothelial progenitor cells

David M. Smadja, Ivan Bièche, Sophie Susen, Laetitia Mauge, Ingrid Laurendeau, Clément D’Audigier, Françoise Grelac, Joseph Emmerich, Martine Aiach, Pascale Gaussem

Journal:

Journal of Cellular and Molecular Medicine

Year:

2009

Language:

english

File:

PDF, 1.04 MB

english, 2009

39

No influence of the VAMP8 rs1010 single nucleotide polymorphism on platelet functions in vitro

Pascale Gaussem, Brian Y. Ishida, Pierre Fontana, Clive R. Pullinger, John P. Khane, Martine Aiach, Christilla Bachelot-Loza, Sophie Gandrille

Journal:

Journal of Cellular and Molecular Medicine

Year:

2009

Language:

english

File:

PDF, 970 KB

english, 2009

40

Human thrombin variable region 1, including E39, is involved in interactions with α1-antitrypsin M358R and protein C

Pascale Gaussem, Véronique Picard, Gilliane Chadeuf, Emmanuel Arnaud, Martine Aiach

Journal:

Year:

1995

Language:

english

File:

PDF, 350 KB

english, 1995

41

Amino acids 225–235 of the protein C serine-protease domain are important for the interaction with the thrombin-thrombomodulin complex

A. Vincenot, P. Gaussem, J.L. Pittet, S. Debost, M. Aiach

Journal:

Year:

1995

Language:

english

File:

PDF, 456 KB

english, 1995

42

Thrombopénie ferriprive : un diagnostic différentiel rare du purpura thrombopénique auto-immun

S. Chaker, S. Very, D. Helley, P. Gaussem, J. Pouchot, L. Darnige, A.-M. Fischer, L. Capron, J.-B. Arlet

Journal:

La Revue de Médecine Interne

Year:

2010

File:

PDF, 196 KB

2010

43

Étude pilote sur la réponse à l’aspirine et la réponse au clopidogrel chez des patients âgés

E. Pautas, T. Belleville, P. Gaussem, JL. Golmard, L. Raymond, J. Szymezak, V. Siguret, I. Gouin-Thibault

Journal:

La Revue de Médecine Interne

Year:

2011

Language:

french

File:

PDF, 84 KB

french, 2011

44

High on-clopidogrel platelet reactivity: Genotyping Can help to optimize antiplatelet treatment

Jean Szymezak, Caroline Moreau, Marie-Anne Loriot, Eric Durand, Hubert Van Viet, Michel Desnos, Pascale Gaussem

Journal:

Thrombosis Research

Year:

2011

Language:

english

File:

PDF, 417 KB

english, 2011

45

A monoclonal antibody recognizing the activation domain of protein C in its calcium-free conformation

Anne Vincenot, Jean-Louis Pittet, Martine Aiach, Pascale Gaussem

Journal:

Year:

1998

Language:

english

File:

PDF, 147 KB

english, 1998

46

Expression and Characterization of Recombinant Protein S with the Ser 460 Pro Mutation

Olivier Morbœuf, Delphine Borgel, Martine Aiach, Tahar Kaabache, Sophie Gandrille, Pascale Gaussem

Journal:

Thrombosis Research

Year:

2000

Language:

english

File:

PDF, 104 KB

english, 2000

47

RESPONSE TO DDAVP STIMULATION IN THIRTEEN PATIENTS WITH BUERGER'S DISEASE.

V Siguret, M Alhenc-Gelas, M Aiach, J.N Fiessinger, P Gaussem

Journal:

Thrombosis Research

Year:

1997

Language:

english

File:

PDF, 446 KB

english, 1997

48

Surveillance d’un traitement par la tinzaparine à dose curative pendant dix jours chez le sujet âgé

E Pautas, V Siguret, M d’Urso, M Laurent, P Gaussem, M Février, B Durand-Gasselin

Journal:

La Revue de Médecine Interne

Year:

2001

Language:

french

File:

PDF, 115 KB

french, 2001

49

Delivery management in a woman with thrombocytopenia of the May–Hegglin anomaly type

Habib Chabane, Yves Gallais, Dominique Pathier, Gil Tchernia, Pascale Gaussem

Journal:

European Journal of Obstetrics & Gynecology and Reproductive Biology

Year:

2001

Language:

english

File:

PDF, 47 KB

english, 2001

50

Purinergic receptor P2Y, G-protein coupled, 12 gene variants and risk of incident ischemic stroke, myocardial infarction, and venous thromboembolism

Robert Y.L. Zee, Sherri E. Michaud, Kirsti A. Diehl, Daniel I. Chasman, Joseph Emmerich, Pascale Gaussem, Martine Aiach, Paul M. Ridker

Journal:

Atherosclerosis

Year:

2008

Language:

english

File:

PDF, 101 KB

english, 2008

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